Genetics of New-Onset Post Transplant Diabetes Mellitus (NOPTDM)
The development of diabetes after transplantation is a significant problem that dramatically increases patient morbidity and mortality. The principle cause of NOPTDM is the use of diabetogenic drugs, especially steroids and calcineurin inhibitors (CNIs), and yet only a proportion of recipients develop the disease. This suggests an individuality in susceptibility that may have a genetic component.
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